Anti-CCDC88A

Anti-CCDC88A
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-102A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A303-102A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling... more
Product information "Anti-CCDC88A"
Protein function: Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)- dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation. Essential for the integrity of the actin cytoskeleton and for cell migration (PubMed:16139227). Required for formation of actin stress fibers and lamellipodia (PubMed:15882442). May be involved in membrane sorting in the early endosome (PubMed:15882442). Plays a role in ciliogenesis and cilium morphology and positioning and this may partly be through regulation of the localization of scaffolding protein CROCC/Rootletin (PubMed:27623382). [The UniProt Consortium]
Keywords: Anti-APE, Anti-GIV, Anti-HkRP1, Anti-Girdin, Anti-CCDC88A, Anti-Hook-related protein 1, Anti-Girders of actin filament, Anti-Akt phosphorylation enhancer, Anti-Coiled-coil domain-containing protein 88A, Anti-G alpha-interacting vesicle-associated protein
Supplier: Bethyl Laboratories
Supplier-Nr: A303-102A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse)
Immunogen: synthetic peptide. The epitope recognized by A303-102A maps to a region between residue 1425 and 1475 of human Coiled-Coil Domain Containing 88A using the numbering given in entry NP_001129069.1 (GeneID 55704).
Format: Antigen Affinity Purified

Database Information

UniProt ID : Q3V6T2 | Matching products
Gene ID GeneID 55704 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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