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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| A303-616A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
| A303-616A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Transcriptional corepressor which facilitates transcriptional repression via... more
Product information "Anti-CBFA2T3"
Protein function: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Reduces the protein levels and stability of the transcriptinal regulator HIF1A, interacts with EGLN1 and promotes the HIF1A prolyl hydroxylation-dependent ubiquitination and proteasomal degradation pathway (PubMed:25974097). Contributes to inhibition of glycolysis and stimulation of mitochondrial respiration by down-regulating the expression of glycolytic genes including PFKFB3, PFKFB4, PDK1, PFKP, LDHA and HK1 which are direct targets of HIF1A (PubMed:23840896, PubMed:25974097). Regulates the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes. Plays a role in granulocyte differentiation (PubMed:15231665). [The UniProt Consortium]
| Keywords: | Anti-MTG16, Anti-hMTG16, Anti-CBFA2T3, Anti-Protein CBFA2T3, Anti-MTG8-related protein 2, Anti-Zinc finger MYND domain-containing protein 4, Anti-Myeloid translocation gene on chromosome 16 protein |
| Supplier: | Bethyl Laboratories |
| Supplier-Nr: | A303-616A |
Properties
| Application: | WB, IP |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human (Expected: orangutan, gorilla, chimpanzee, northern white-cheeked gibbon) |
| Immunogen: | Synthetic peptide. The epitope recognized by A303-616A maps to a region between residue 603 and 653 of human Core-Binding Factor, Runt Domain, alpha subunit 2, translocated to, 3 using the numbering given in entry NP_005178.4 (GeneID 863). |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K22752 | Matching products |
| UniProt ID : | O75081 | Matching products |
| Gene ID | GeneID 863 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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