Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase 9, and caspase 2. A novel CARD...

Bcl-9 (B-cell lymphoma 9, also Protein legless homolog) is a 149kD transcriptional regulator that belongs to the Bcl-9 family of proteins. It is expressed in multiple tissues and serves to recruit Pygopus to the Wnt-pathway beta-catenin-TCF complex in the nucleus. Bcl-9 and Bcl-9-2 are considered evolutionary...

B cell CLL/leukemia 10 (Bcl-10), a 233 amino acid, 26.2kD protein, is the cellular homolog of the equine Herpes virus-2 gene (E10). Bcl-10 is also known as CARD like apoptotic protein (CLAP), CED-3/ICH-1 prodomain homologous E10-like regulator (CIPER), celluar-E10 (c-E10), and CARD-containing molecule enhancing...

Applications: , Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.5ug/ml for HRPO/ECL detection. Recommended blocking buffer: BSA/Tween20., Optimal dilutions to be determined by the researcher. Positve Control Included: B0807-12F1: Bcl 10, phosphorylated...

Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing...