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Name/Antigen KLON WIRT TYP ISOTYP SPEZ. REAKT. FORMAT ANWENDUNG HERSTELLER KAT # MENGE PREIS










Anti-​BRAP
Rabbit
> sec. Ab
Pab IgG
human
Erklärungen der Abkürzungen ansehen.
antigen affinity purified WB
IPErklärungen der Abkürzungen ansehen.
Bethyl
Icon Datasheet
A302-​682A

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100 µl

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349 €
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Anti-BRAP


BRCA1-​associated protein (BRAP) negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. BRAP acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-​polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. BRAP may also act as a cytoplasmic retention protein with a role in regulating nuclear transport. Alternative names for BRAP include BRAP2, impedes mitogenic signal propagation, IMP, RING finger protein 52, renal carcinoma antigen NY-​REN-​63, and RNF52. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7Z569]
Immunogen: synthetic peptide. The epitope recognized by A302-​682A maps to a region between residue 560 and 592 of human BRCA1 associated protein using the numbering given in entry NP_006759.3 (GeneID 8315).


Datenblatt ansehen

Kat #: A302-682A


Menge:
100 µl

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Preis:
349 €

UniProt ID: Q7Z569 (Protein knowledgebase)
Geninformationen: GeneID 8315

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Schlagworte:
EC=6.3.2.-​, Anti-​BRAP, Anti-​BRCA1 associated protein, Anti-​IMP, Anti-​impedes mitogenic signal propagation, Anti-​RNF52, Anti-​RING finger protein 52., antibody, antibodies, Antikörper

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    Products for: BRAP - BRCA1-associated protein [EC:6.3.2.19]




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