Anti-BCoR

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-672A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A301-672A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Transcriptional corepressor. May specifically inhibit gene expression when... more

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Product information "Anti-BCoR"

Protein function: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence- specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A, impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2). [The UniProt Consortium]

Keywords:	Anti-BCOR, Anti-BCoR, Anti-KIAA1575, Anti-BCL-6 corepressor
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-672A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: rat, bovine, dog, horse, rabbit, guinea pig, swine, panda, orangutan, gorilla, white-tufted-ear marmoset, chinese hamster, naked mole rat, thirteen-lined ground squirrel, little brown bat, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-672A maps to a region between residue 25 and 75 of human BCL6 co-repressor using the numbering given in entry EAW59426.1 (GeneID 54880).
Format:	Antigen Affinity Purified