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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-G82 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-BACE2 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-BACE2"
Anti-BACE2 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with BACE2 with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with BACE2 from other sources has not been determined. BACE2 antibody detects human amyloid-beta (Abeta) plaque. Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Abeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) at beta- and gamma-sites by proteases. The long-sought beta-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2). A BACE homolog was recently cloned and designated BACE2, Asp1, DRAP (for Down region aspartic protease), and memapsin 1. BACE2 also cleaves APP at beta-site and at a different site within Abeta. BACE2 locates on chromosome 21q22.3, the so-called 'Down critical region', suggesting that BACE2 and Abeta may also contribute to the pathogenesis of Down syndrome. Anti-BACE2 antibodies are ideal for investigators involved in Neuroscience and DNA Damage and Repair.
Keywords: | Anti-ASP1, Anti-DRAP, Anti-AEPLC, Anti-ASP21, Anti-ALP56, Anti-BACE2, Anti-Asp 1, EC=3.4.23.45, Anti-Memapsin-1, Anti-Theta-secretase, Anti-Beta-secretase 2, Anti-Aspartyl protease 1, Anti-Aspartic-like protease 56 kDa |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-G82 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | synthetic peptide corresponding to an internal region of human BACE2. |
Format: | Purified |
Database Information
KEGG ID : | K07747 | Matching products |
UniProt ID : | Q9Y5Z0 | Matching products |
Gene ID | GeneID 25825 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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