- Search results for A300-752A
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25 products were found matching "A300-752A"!
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Item number: A300-275A-T
Protein function: Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of...
Keywords: | Anti-KAP1, Anti-KAP-1, Anti-TRIM28, Anti-KRIP-1, Anti-TIF1-beta, EC=6.3.2.-, Anti-RING finger protein 96,... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-572A-T
Protein function: Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates...
Keywords: | Anti-Bloom syndrome protein homolog |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-725A-T
Protein function: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription...
Keywords: | Anti-Transcriptional corepressor Sin3a, Anti-Paired amphipathic helix protein Sin3a, Anti-Histone deacetylase complex... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A300-052A-T
Mediator of DNA damage checkpoint protein 1 (Mdc1) is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It may serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage...
Keywords: | Anti-MDC1, Anti-KIAA0170, Anti-Nuclear factor with BRCT domains 1, Anti-Mediator of DNA damage checkpoint protein 1 |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human |
164.00€
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Item number: A300-772A-T
Fidgetin-like protein 1 (FIGNL1) is a member of the ATPases associated with diverse cellular activities (AAA proteins) subfamily of proteins. The function of FIGNL1 has not been determined but it may play a role in osteoblastogenesis. Protein function: Involved in DNA double-strand break (DBS) repair via homologous...
Keywords: | Anti-FIGNL1, EC=3.6.4.-, Anti-Fidgetin-like protein 1 |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
164.00€
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Item number: A300-782A
Protein function: Required for innate immune defense against viruses. Acts downstream of DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral...
Keywords: | Anti-VISA, Anti-MAVS, Anti-IPS1, Anti-IPS-1, Anti-Cardif, Anti-Virus-induced-signaling adapter, Anti-CARD adapter inducing... |
Application: | WB, IP, IHC, ICC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A300-652A
Protein function: Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis (PubMed:12364621, PubMed:22553214, PubMed:23333306, PubMed:17190600, PubMed:21144835, PubMed:28241136). Plays a key role in the repair of...
Keywords: | Anti-phospho-53BP1, Anti-phospho-p53BP1, Anti-phospho-p53-binding protein 1, Anti-phospho-TP53-binding protein 1 |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-452A
Protein function: Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2- MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields...
Keywords: | Anti-MSH2, Anti-hMSH2, Anti-MutS protein homolog 2, Anti-DNA mismatch repair protein Msh2 |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-052A
Protein function: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of...
Keywords: | Anti-MDC1, Anti-KIAA0170, Anti-Nuclear factor with BRCT domains 1, Anti-Mediator of DNA damage checkpoint protein 1 |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human |
588.00€
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Item number: A300-352A
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor...
Keywords: | Anti-E6AP, Anti-UBE3A, EC=2.3.2.26, Anti-Ubiquitin-protein ligase E3A, Anti-E6AP ubiquitin-protein ligase, Anti-Renal... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A300-712A
Protein function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone...
Keywords: | Anti-HD1, Anti-HDAC1, Anti-RPD3L1, EC=3.5.1.98, Anti-Histone deacetylase 1 |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A300-852A-T
Protein function: Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial...
Keywords: | Anti-HURP, Anti-DLG7, Anti-DAP-5, Anti-DLGAP5, Anti-Discs large homolog 7, Anti-Hepatoma up-regulated protein, Anti-Disks... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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