- Search results for Cay13737-1
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4 products were found matching "Cay13737-1"!
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Item number: Cay37371-1
Cucurbitacin IIa is a triterpenoid that has been found in H. amabilis and has diverse biological activities. It decreases the proliferation of (IC50 = 370 nM), and induces cell cycle arrest at the G2/M phase and apoptosis in, HT-29 colorectal adenocarcinoma cells when used at a concentration of 1 µM. Cucurbitacin...
Keywords: | Dihydrocucurbitacin Q1, Hemslecin A,... |
Application: | Bioactive triterpenoid |
CAS | 58546-34-2 |
MW: | 562.7 D |
From 90.00€
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Item number: Cay13731-1
Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination, and methylation. These modifications play critical roles in regulating chromatin structure and gene...
Keywords: | Anti-SETD7, Anti-SET7/9, EC=2.1.1.43, Anti-KIAA1717, Anti-H3-K4-HMTase SETD7, Anti-Lysine N-methyltransferase 7, Anti-SET... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
432.00€
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Item number: Cay13371-1
CAY10621 is an inhibitor of sphingosine kinase 1 (SPHK1, IC50 = 3.3 µM). It is selective for SPHK1 over SPHK2 at 10 µM and PKC at concentrations less than 100 µM. CAY10621 inhibits SPHK1 activity by 70% in U937 cells when used at a concentration of 5 µM.Formal Name:...
Keywords: | SKI 5C, SPHK1 Inhibitor 5C, (4S)-2,2-dimethyl-4-(1-oxo-2-hexadecyn-1-yl)-3-oxazolidinecarboxylic acid, 1,1-dimethylethyl... |
Application: | SPHK 1 inhibitor |
CAS | 120005-55-2 |
MW: | 435.6 D |
From 38.00€
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Item number: Cay17371-1
Toyocamycin is a natural adenosine analog first isolated from Streptomyces and shown in early studies to be cytotoxic to bacteria, fungi, and cancer cells and to have antiviral activities. Toyocamycin prevents IRE1alpha-induced mRNA cleavage (IC50 = 80 nM) and inhibits constitutive activation of XBP1 in multiple...
Keywords: | NSC 63701, NSC 99843, 4-amino-7-beta-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, hydrate |
Application: | Natural adenosine analog, IRE1alpha-induced mRNA cleavage inhibitor |
MW: | 291.3 D |
From 43.00€
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