Anti-ASAH2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-Y66	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-ASAH2 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-ASAH2"

Anti-ASAH2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ASAH2 from other sources has not been determined. Protein function: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract. [The UniProt Consortium]

Keywords:	Anti-HNAC1, Anti-ASAH2, EC=3.5.1.23
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-Y66

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	17 amino acid synthetic peptide near the C-terminus of the human ASAH2.
Format:	Purified