Anti-AML1 ETO

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BPS-25208	100 µl		-	-	3 - 15 business days*		873.00€

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The AML1 (RUNX1) (UniProtKB/Swiss-Prot entry Q01196) - ETO (RUNX1T1) (UniProtKB/Swiss-Prot entry... more

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Product information "Anti-AML1 ETO"

The AML1 (RUNX1) (UniProtKB/Swiss-Prot entry Q01196) - ETO (RUNX1T1) (UniProtKB/Swiss-Prot entry Q06455) fusion protein arises due to a translocation between chromosome 8 and 22 (t(8,21)(q22,q22)). This translocation is one of the most frequent karyotypic abnormalities observed in acute myeloid leukaemia. It produces a chimerical gene made up of the 5'-region of AML1and the 3'-region of ETO. The chimerical protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.

Keywords:	Anti-AML1T1, Anti-RUNX1T1, Anti-Protein ETO, Anti-Protein MTG8, Anti-Protein CBFA2T1, Anti-Eight twenty one protein, Anti-Cyclin-D-related protein, Anti-Zinc finger MYND domain-containing protein 2,
Supplier:	BPS Bioscience
Supplier-Nr:	25208

Properties

Application:	ChIP/ChIP-seq, ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Species reactivity:	human
Immunogen:	AML1 ETO fusion protein using a KLH conjugated synthetic peptide.
Format:	Serum