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Anti-AKT3, clone 25F6.F6.D8

ART NR.: 200-301-E75 (100 µg)
200-301-E75S (25 µl)

Hersteller: Rockland

Datenblatt

Anwendungen: ELISA, WB

Format: purified

Klon: 25F6.F6.D8

Wirt: Mouse

Isotyp: IgG1

Reaktivität: human

Immunogen: synthetic peptide corresponding to internal residues of human AKT3 protein

UniProt ID: Q9Y243
Suche mit UniProt ID

Geninformationen: GeneID 10000

Schlagworte: Anti-AKT3, Anti-PKBG, Anti-STK-2, Anti-PKB gamma, EC=2.7.11.1, Anti-RAC-PK-gamma, Anti-Protein kinase Akt-3, Anti-Protein kinase B gamma, Anti-RAC-gamma serine/threonine-protein kinase

25 µl

114 €

102 €

100 µg

371 €

333 €
Größe wählen:
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Bemerkungen: Protein function: AKT3 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase- dependent apoptosis. [The UniProt Consortium]

Die Preise für Antikörper verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.





 


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