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Anti-AKT3, clone 25F6.F6.D8

ART NR.: 200-301-E75S (25 µl)
200-301-E75 (100 µg)

Hersteller: Rockland


Anwendungen: ELISA, WB

Format: purified

Klon: 25F6.F6.D8

Wirt: Mouse

Isotyp: IgG1

Reaktivität: human (expected: mouse, rat)

Immunogen: synthetic peptide corresponding to internal residues of human AKT3 protein

Lagerung: -20°C

Versand: -20°C

UniProt ID: Q9Y243 | Suche mit UniProt ID

Gene ID: Gene ID 10000 | Suche mit Gene ID

KEGG ID: K04456 | Suche mit KEGG ID

Schlagworte: Anti-AKT3, Anti-PKBG, Anti-STK-2, Anti-PKB gamma, EC=, Anti-RAC-PK-gamma, Anti-Protein kinase Akt-3, Anti-Protein kinase B gamma, Anti-RAC-gamma serine/threonine-protein kinase


25 µl

121 €

108 €

100 µg

407 €

366 €
Größe wählen:
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Bemerkungen: Protein function: AKT3 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase- dependent apoptosis. [The UniProt Consortium]


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