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1 Antikörper Treffer
Rubrik: Modifikation:
Name/Antigen KLON WIRT TYP ISOTYP SPEZ. REAKT. FORMAT ANWENDUNG HERSTELLER KAT # MENGE PREIS










Anti-​AKT3, clone 25F6.F6.D8
25F6.F6.D8 Mouse
> sec. Ab
Mab IgG1
human

expected: mouse, rat
Erklärungen der Abkürzungen ansehen.
purified ELISA
WBErklärungen der Abkürzungen ansehen.
Rockland
Icon Datasheet
200-​301-​E75 100 µg

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371 €
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Anti-AKT3, clone 25F6.F6.D8


Protein function: AKT3 is one of 3 closely related serine/threonine-​ protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-​regulation and down-​regulation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-​induced increases in cellular energy demands. Down-​regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase-​ dependent apoptosis. [The UniProt Consortium]
Immunogen: synthetic peptide corresponding to internal residues of human AKT3 protein


Datenblatt ansehen

Kat #: 200-301-E75


Menge:
100 µg

Buy Bulk


Preis:
371 €
333 €

save money!


UniProt ID: Q9Y243 (Protein knowledgebase)
Geninformationen: GeneID 10000

Antikörper-Konjugations-Kits

Schlagworte:
Anti-​AKT3, Anti-​PKBG, Anti-​STK-​2, Anti-​PKB gamma, EC=2.7.11.1, Anti-​RAC-​PK-​gamma, Anti-​Protein kinase Akt-​3, Anti-​Protein kinase B gamma, Anti-​RAC-​gamma serine/threonine-​protein kinase, antibody, antibodies, Antikörper

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Products for: AKT - RAC serine/threonine-protein kinase [EC:2.7.11.1]



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