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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
200-301-D05 | 100 µl | - | - |
6 - 10 business days* |
698.00€
|
Anti-ABCA4 antibody is directed against bovine ABCA4 Rim Protein. The antibody was Protein G... more
Product information "Anti-ABCA4 (Rim Protein), clone 3F4"
Anti-ABCA4 antibody is directed against bovine ABCA4 Rim Protein. The antibody was Protein G purified from culture supernatant. Reactivity is expected against human, mouse and Xenopus. Cross-reactivity with ABCA4 from other sources has not been determined. Protein function: In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans- retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery. [The UniProt Consortium]
Keywords: | Anti-RmP, Anti-Abcr, Anti-Abca4, Anti-RIM protein, Anti-RIM ABC transporter, Anti-ATP-binding cassette sub-family A member 4, Anti-Retinal-specific ATP-binding cassette transporter |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 200-301-D05 |
Properties
Application: | ELISA, IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 3F4 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | bovine, human, mouse, Xenopus |
Immunogen: | partially purified bovine 220-kDa disc rim protein. |
Format: | Purified |
Database Information
KEGG ID : | K05644 | Matching products |
UniProt ID : | O35600 | Matching products |
Gene ID | GeneID 11304 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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