Anti-ABCA4 (Rim Protein), clone 3F4

Anti-ABCA4 (Rim Protein), clone 3F4
Item number Size Datasheet Manual SDS Delivery time Quantity Price
200-301-D05 100 µl - -

6 - 10 business days*

698.00€
 
Anti-ABCA4 antibody is directed against bovine ABCA4 Rim Protein. The antibody was Protein G... more
Product information "Anti-ABCA4 (Rim Protein), clone 3F4"
Anti-ABCA4 antibody is directed against bovine ABCA4 Rim Protein. The antibody was Protein G purified from culture supernatant. Reactivity is expected against human, mouse and Xenopus. Cross-reactivity with ABCA4 from other sources has not been determined. Protein function: In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans- retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery. [The UniProt Consortium]
Keywords: Anti-RmP, Anti-Abcr, Anti-Abca4, Anti-RIM protein, Anti-RIM ABC transporter, Anti-ATP-binding cassette sub-family A member 4, Anti-Retinal-specific ATP-binding cassette transporter
Supplier: Rockland Immunochemicals
Supplier-Nr: 200-301-D05

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 3F4
Conjugate: No
Host: Mouse
Species reactivity: bovine, human, mouse, Xenopus
Immunogen: partially purified bovine 220-kDa disc rim protein.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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