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Anti-4EBP1

ART NR.: A300-501A (100 µl)

Hersteller: Bethyl

Datenblatt

Anwendungen: WB

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human, swine, mouse, rat (expected: rabbit, orangutan, rhesus monkey, gorilla, chimpanzee, crab-eating macaque, chinese hamster, thirteen-lined ground squirrel)

Immunogen: synthetic peptide. The epitope recognized by A300-501A maps to a region between residue 75 and the C-terminus (residue 118) of human eukaryotic translation initiation factor 4E binding protein 1 using the numbering given in entry NP_004086.1 (GeneID 1978)

UniProt ID: Q13541
Suche mit UniProt ID

Schlagworte: Anti-eIF-4EBP-1, Anti-PHAS-I, Anti-4E-BP1, Anti-PHAS

A300-501A

100 µl

349 €

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Bemerkungen: Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) binds directly to eIF4E to inhibit complex assembly for translation initiation. 4EBP1 is part of a family of translation repressor proteins. 4EBP1 is directly phosphorylated by the mTORC1 complex during growth factor stimulation of cells. Phosphorylation of 4EBP1 causes its release from eIF4E to allow translation to proceed. 4EBP1 is also called eIF4E-binding protein, phosphorylated heat-and-acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1, BP-1, and MGC4316.

Spezifikationen

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