4 products were found matching "0004-18D.100"!

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Anti-4E Binding Protein-1 (4E-BP1, PHAS-1)
Anti-4E Binding Protein-1 (4E-BP1, PHAS-1)

Item number: 0004-18.100

4E-BP1 (also known as PHAS-1) normally binds eIF4E, inhibiting cap-dependent translation. Hyperphosphorylation of 4E-BP1 disrupts this binding, activating cap-dependent translation (1). The PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 (2,3). 4E-BP1 is phosphorylated in vivo on multiple residues (4),...
Keywords: Anti-4E-BP1, Anti-PHAS
Application: IP, WB
Host: Rabbit
Species reactivity: human, monkey, mouse, rat
659.00€ *
Review
4E Binding Protein 1 (4E-BP1) Blocking Peptide
4E Binding Protein 1 (4E-BP1) Blocking Peptide

Item number: 0004-18E.100

Peptide is used to block 4E-BP1 Rabbit mAb reactivity in immunohistochemistry protocols. Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the eIF4E translation initiation factor. Hyperphosphorylation of 4E-BP1 disrupts this interaction and cap-dependent...
Application: IHC
431.00€ *
Review
Anti-phospho-4E Binding Protein 1,  (Thr37/46) (Protein Synthesis Initiation Factor 4E Binding
Anti-phospho-4E Binding Protein 1, (Thr37/46) (Protein...

Item number: 0004-18J.100

When bound to eIF4E, 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation. Upon hyperphosphorylation of 4E-BP1 this interaction is disrupted and cap-dependent translation is activated (1). Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity (2,3). Multiple 4E-BP1 residues are...
Keywords: Anti-phospho-4E-BP1, Anti-phospho-PHAS-I, Anti-phospho-Eif4ebp1, Anti-phospho-eIF4E-binding protein 1,...
Application: FC, ICC, IF, IHC, WB
Host: Rabbit
Species reactivity: drosophila, human, monkey, mouse, rat
711.00€ *
Review
Anti-4E Binding Protein 1 (Protein Synthesis Initiation Factor 4E Binding Protein, eIF-4EBP1, PHAS-1
Anti-4E Binding Protein 1 (Protein Synthesis Initiation...

Item number: 0004-18F.100

PHAS-I, also known as eIF4E-BP1 and PHAS-II,-III (eIF4E-BP2, 3), are members of a family of proteins that regulate eukaryotic translation initiation which is mediated by the cap structure (m7GpppN, where N=any nucleotide) present at the 5í end of all cellular mRNAs, except organellar (1). The m7 cap is essential for...
Application: IHC, WB
Host: Rabbit
Species reactivity: human
477.00€ *
Review