Anti-4E-BP1

Anti-4E-BP1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
029924.100 100 µl - -

3 - 19 business days*

796.00€
 
4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1),also called... more
Product information "Anti-4E-BP1"
4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I ,which is located on chromosome 8p12, with 118-amino acid protein (about 13kD). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while(24kD), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction. Applications: Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: 029924

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 13B2
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Purified recombinant fragment of 4E-BP1 expressed in E. coli.
Purity: Ascites

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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