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Anti-BRAF (IHC)

ART NR.: IHC-00607 (100 µl)

Hersteller: Bethyl

Datenblatt

Anwendungen: IHC

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human

Immunogen: synthetic peptide. The epitope recognized by IHC-00607 maps to a region between residue 25 and 75 of human v-raf murine sarcoma viral oncogene homolog B1 using the numbering given in entry NP_004324.2 (GeneID 673).

UniProt ID: P15056
Suche mit UniProt ID

Geninformationen: GeneID 673

Schlagworte: Anti-p94, Anti-BRAF, Anti-BRAF1, EC=2.7.11.1, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf, Anti-v-Raf murine sarcoma viral oncogene homolog B1

100 µl

401 €

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Bemerkungen: B-Raf proto-oncogene serine/threonine-protein kinase (BRAF) is a member of the raf/mil family of serine/threonine kinases. BRAF is involved in transducing mitogenic signals via the MAP kinase/ERKs signaling pathway. Mutations in BRAF are involved in a wide range of cancers such as lung, non-Hodgkin lymphoma, and colorectal cancer. Defects in BRAF are also the cause of cardiofaciocutaneous syndrome (CFC), an autosomal dominant syndrome characterized by facial anomalies, heart defects, and ectodermal abnormalities. Alternate names for BRAF include murine sarcoma viral (v-raf) oncogene homolog B1, 94 kDa B-raf protein, RAFB1, and B-RAF1.

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