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Anti-MEK1

ART NR.: A302-140A (100 µl)

Hersteller: Bethyl

Datenblatt

Anwendungen: WB

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human

Immunogen: synthetic peptide. The epitope recognized by A302-140A maps to a region between residue 343 and 393 of human MAPK/ERK kinase 1 (Dual specificity mitogen-activated protein kinase kinase 1) using the numbering given in entry NP_002746.1 (GeneID 5604).

UniProt ID: Q02750
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Geninformationen: GeneID 5604

Schlagworte: EC=2.7.12.2, Anti-MEK1, Anti-MEK-1, Anti-MAPK/ERK kinase 1, Anti-MAP2K1, Anti-MKK1, Anti-MAPKK1, Anti-Dual specificity mitogen-activated protein kinase kinase 1, Anti-PRKMK1, : protein kinase, mitogen-activated, kinase 1.

100 µl

349 €

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Bemerkungen: MEK1 is an activator and kinase for MAP and ERK kinases. It is a serine/threonine kinase essential to the MAP kinase signal transduction pathway which is involved in a multitude of cellular processes such as proliferation, differentiation, gene activation, and development. MEK1 displays 85 percent identity with MEK2. Although MEK1 and MEK2 have been found to be functionally similar, they may serve non-redundant functions. Both are required for cellular proliferation and may play a role in tumorigenesis. Alternative names for MEK1 include dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK1, MAP2K1, and PRKMK1.

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