SMRT (silencing mediator of retinoid and thyroid hormone receptor) mediates gene repression by interacting with nuclear receptors such as the thyroid hormone receptor, retinoic acid receptor, progesterone receptor, androgen receptor, estrogen receptor, and glucocorticoids receptor. SMRT mediates repression by associating with SIN3A/B and the histone deacetylases, HDAC1 and HDAC2, and promoting the formation of repressive chromatin structures. Alternate names for SMRT include SMRTE, SMRTE-tau, silencing mediator for retinoid and thyroid hormone receptors, NCoR2, NCoR-2, nuclear receptor co-repressor 2, TRAC1, TRAC-1, Thyroid- retinoic-acid-receptor-associated corepressor, T3 receptor-associating factor, TNRC14, and SMAP270.
Immunogen: synthetic peptide. The epitope recognized by A301-147A maps to a region between residue 1525 and 1575 of human silencing mediator of retinoic acid and thyroid hormone receptor alpha using the numbering given in entry AAD20946.1 (GeneID 9612).
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Kat #: A301-147A
Menge: 100 µlBuy Bulk
Preis: 343 €
UniProt ID: Q9Y618 (Protein knowledgebase)
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Schlagworte:
Anti-SMRT, Anti-TRAC, Anti-NCOR2, Anti-CTG26, Anti-N-CoR2, Anti-SMAP270, Anti-CTG repeat protein 26, Anti-Nuclear receptor corepressor 2, Anti-T3 receptor-associating factor, Anti-Thyroid-, retinoic-acid-receptor-associated corepressor, antibody, antibodies, Antikörper Loading ...
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