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Anti-PTEN

ART NR.: A300-701A (100 µl | 20 µg)

Hersteller: Bethyl

Datenblatt

Anwendungen: WB, IP

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human, mouse (expected: chicken, turkey, bovine, dog, horse, rabbit, guinea pig, swine, panda, orangutan, rhesus monkey, gorilla, chimpanzee, duckbill platypus, tasmanian devil, white-tufted-ear marmoset, domestic water buffalo)

Immunogen: synthetic peptide. The epitope recognized by A300-701A maps to a region between residue 350 and the C-terminus (residue 403) of human phosphatase and tensin homolog using the numbering given in entry NP_000305.2 (GeneID 5728).

Lagerung: +4°C

Versand: +4°C

UniProt ID: P60484 | Suche mit UniProt ID

KEGG ID: K01110 | Suche mit KEGG ID

Schlagworte: EC=3.1.3.67, EC=3.1.3.16, EC=3.1.3.48, Anti-PTEN, Anti-phosphatase and tensin homolog, Anti-MMAC1, Anti-MMAC-1, Anti-Mutated in Multiple Advanced Cancers 1, Anti-MHAM, Anti-TEP1

A300-701A

100 µl (20 µg)

459 €

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Bemerkungen: PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling. PTEN is also known as mutated in multiple advanced cancers 1, MMAC1, TEP1, BZS, MHAM, and MGC11227.

Spezifikationen

PTEN Antibody

Rabbit anti-PTEN Antibody, Affinity Purified
PTEN AntibodyPTEN AntibodyPTEN Antibody
PTEN AntibodyPTEN AntibodyPTEN Antibody

Gene and Protein Information

Citations

Wan X et al., Oxidative inactivation of the lipid phosphatase phosphatase and tensin homolog on chromosome ten (PTEN) as a novel mechanism of acquired long QT syndrome. J Biol Chem. 2011 Jan 28;286(4):2843-52. IP
PubMed: 21097842

Verwandte Produkte

Products for: PTEN - phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]

Die Preise für Antikörper verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.



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