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Anti-Raptor

ART NR.: A300-506A (100 µl)

Hersteller: Bethyl

Datenblatt

Anwendungen: WB

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human, rat, mouse

Immunogen: synthetic peptide. The epitope recognized by A300-506A maps to a region between residues 975 and 1025 of human Regulatory associated protein of mTOR using the numbering given in entry AAM09075.1 (GeneID 57521)

UniProt ID: Q8N122
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Schlagworte: Anti-Raptor, Anti-regulatory associated protein of mTOR, Anti-p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, Anti-KIAA1303.

100 µl

386 €

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Bemerkungen: Raptor (regulatory-associated protein of mTOR) is part of the rapamycin sensitive mTORC1 complex which includes mTOR, and mLst8/GbetaL. S6K and 4EBP1 are substrates of mTORC1 kinase activity. Raptor is required for mTOR´s ability to phosphorylate 4E-BP1 and physically interacts with 4EBP1 to act as a potential scaffold that bridges mTOR and 4EBP1 or S6K. The mTORC1 complex integrates cell signals to promote cell growth in response to growth factors. Raptor is also known as P150 target of rapamycin (TOR)-scaffold protein, and KIAA1303.

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