PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling. PTEN is also known as mutated in multiple advanced cancers 1, MMAC1, TEP1, BZS, MHAM, and MGC11227.
Immunogen: synthetic peptide. The epitope recognized by A300-024A maps to a region between residue 350 and the C-terminus (residue 403) of human phosphatase and tensin homolog using the numbering given in entry NP_000305.2 (GeneID 5728).
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Kat #: A300-024A
Menge: 100 µlBuy Bulk
Preis: 343 €
UniProt ID: P60484 (Protein knowledgebase)
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Schlagworte:
EC=3.1.3.67, EC=3.1.3.16, EC=3.1.3.48, Anti-PTEN, Anti-phosphatase and tensin homolog, Anti-MMAC1, Anti-Mutated in multiple advanced-3,4,5-trisphosphate 3-phosphatase, antibody, antibodies, Antikörper Loading ...
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| Weitere Produkte für dieses Protein:Antibodies
- Anti-phospho-PTEN (Ser229), Kat #: WA-AP3788a
- Anti-phospho-PTEN (Ser294), Kat #: WA-AP3788b
- Anti-phospho-PTEN (Ser362), Kat #: WA-AP3788c
- Anti-phospho-PTEN (Ser370), Kat #: ABD-8A7201.50
- Anti-phospho-PTEN (Ser380), Kat #: WA-AJ1664c
- Anti-phospho-PTEN (Ser380), Kat #: ABD-8A7202.50
- Anti-phospho-PTEN (Ser385), Kat #: WA-AP3800a
- Anti-phospho-PTEN (Ser385), Kat #: ABD-8A0561.50
- Anti-phospho-PTEN (Thr366), Kat #: WA-AP3788d
- Anti-phospho-PTEN (Thr382), Kat #: WA-AP3788e
- more
Enzymes & Proteins
siRNA
Primers
Peptides
- PTEN (PTEN, BZS, MHAM, TEP1, MMAC1, PTEN1, MGC11227, phosphatase and tensin homolog (mutated in multiple advanced cancers 1), tensin homolog, mutated in multiple advanced cancers 1, MMAC1 phosphatase and tension homolog deleted on chromosome 10) (Control , Kat #: P9182-11-P.100
- PTEN Antibody (C-term F279) Blocking Peptide, Kat #: WA-BP8436b
- PTEN Antibody (C-term) Blocking Peptide, Kat #: WA-BP8436c
- PTEN Antibody (N-term) Blocking Peptide, Kat #: WA-BP8436a
Products for: PTEN - phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
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