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Anti-PTEN

ART NR.: A300-024A-T (20 µl / 2 blots)
A300-024A-M (100 µl / 10 blots)
A300-024A (100 µl / 100 µg)

Hersteller: Bethyl

Datenblatt



MSDS

Anwendungen: WB

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human (expected: chicken, turkey, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, duckbill platypus, tasmanian devil, white-tufted-ear marmoset, domestic water buffalo)

Immunogen: synthetic peptide. The epitope recognized by A300-024A-T maps to a region between residue 350 and the C-terminus (residue 403) of human phosphatase and tensin homolog using the numbering given in entry NP_000305.2 (GeneID 5728).

Lagerung: +4°C

Versand: +4°C

UniProt ID: P60484 | Suche mit UniProt ID

Gene ID: Gene ID 5728 | Suche mit Gene ID

KEGG ID: K01110 | Suche mit KEGG ID

Schlagworte: Anti-PTEN, Anti-MMAC1, EC=3.1.3.16, EC=3.1.3.48, EC=3.1.3.67, Anti-Phosphatase and tensin homolog, Anti-Mutated in multiple advanced cancers 1, Anti-Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

A300-024A-T

20 µl (2 blots)

57 €

A300-024A-M

100 µl (10 blots)

260 €

A300-024A

100 µl (100 µg)

356 €

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Bemerkungen: PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling. PTEN is also known as mutated in multiple advanced cancers 1, MMAC1, TEP1, BZS, MHAM, and MGC11227.

Spezifikationen

PTEN Antibody

Rabbit anti-PTEN Antibody, Affinity Purified
PTEN Antibody

Gene and Protein Information

Citations

Wang CY, Steroidogenic Factor 1 (NR5A1) Maintains Centrosome Homeostasis in Steroidogenic Cells by Restricting Centrosomal DNA-Dependent Protein Kinase Activation. Mol Cell Biol. 2013 Feb;33(3):476-84. WB
PubMed: 23166296

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