Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-A62S | 25 µl | - | - |
6 - 10 business days* |
180.00€
|
||
600-401-A62 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
Protein function: Required for nonsense-mediated mRNA decay (NMD), may act in conjunction with... more
Product information "Anti-eIF3S6/Int6"
Protein function: Required for nonsense-mediated mRNA decay (NMD), may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins. Component of the eukaryotic translation initiation factor 3 (eIF- 3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. [The UniProt Consortium]
Keywords: | Anti-eIF3e, Anti-Eif3e, Anti-Eif3s6, Anti-eIF-3 p48, Anti-MMTV integration site 6, Anti-Viral integration site protein INT-6, Anti-Mammary tumor-associated protein INT-6, Anti-Eukaryotic translation initiation factor 3 subunit 6 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-A62 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | mouse (Expected: human, rat, dog, bovine, monkey) |
Immunogen: | synthetic peptide corresponding to a region near the C-terminus of mouse EIF3S6/Int7 |
MW: | 48 kD |
Format: | Affinity Purified |
Database Information
KEGG ID : | K03250 | Matching products |
UniProt ID : | P60229 | Matching products |
Gene ID | GeneID 16341 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed