Anti-eIF3S6/Int6

Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-A62S 25 µl - -

6 - 10 business days*

180.00€
600-401-A62 100 µg - -

6 - 10 business days*

684.00€
 
Protein function: Required for nonsense-mediated mRNA decay (NMD), may act in conjunction with... more
Product information "Anti-eIF3S6/Int6"
Protein function: Required for nonsense-mediated mRNA decay (NMD), may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins. Component of the eukaryotic translation initiation factor 3 (eIF- 3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. [The UniProt Consortium]
Keywords: Anti-eIF3e, Anti-Eif3e, Anti-Eif3s6, Anti-eIF-3 p48, Anti-MMTV integration site 6, Anti-Viral integration site protein INT-6, Anti-Mammary tumor-associated protein INT-6, Anti-Eukaryotic translation initiation factor 3 subunit 6
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-A62

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: mouse (Expected: human, rat, dog, bovine, monkey)
Immunogen: synthetic peptide corresponding to a region near the C-terminus of mouse EIF3S6/Int7
MW: 48 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-eIF3S6/Int6"
Write a review
or to review a product.
Viewed