Anti-phospho-Rock-2 (Rho-associated Protein Kinase-2) (Tyr256)

Anti-phospho-Rock-2 (Rho-associated Protein Kinase-2) (Tyr256)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-998 100 µg - -

6 - 10 business days*

684.00€
 
Protein function: Protein kinase which is a key regulator of actin cytoskeleton and cell... more
Product information "Anti-phospho-Rock-2 (Rho-associated Protein Kinase-2) (Tyr256)"
Protein function: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. [The UniProt Consortium]
Keywords: Anti-phospho-ROCK2, Anti-phospho-ROCK-II, Anti-phospho-KIAA0619, Anti-phospho-p164 ROCK-2, EC=2.7.11.1, Anti-phospho-Rho kinase 2, Anti-phospho-Rho-associated protein kinase 2, Anti-phospho-Rho-associated, coiled-coil-containing protein kinase 2
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-998

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
MW: 164 kD

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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