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Antikörper Treffer 1
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Name/Antigen KLON WIRT TYP ISOTYP SPEZ. REAKT. FORMAT ANWENDUNG HERSTELLER KAT # MENGE PREIS










Anti-​phospho-​Smad3 (Ser423, Ser425)
Rabbit
> sec. Ab
Pab IgG
human

expected: Xenopus laevis, Xenopus tropicalis, zebrafish, rat, mouse, swine, bovine, chi
Erklärungen der Abkürzungen ansehen.
ELISA
WB
IHC
FCErklärungen der Abkürzungen ansehen.
Rockland
Icon Datasheet
600-​401-​919

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100 µg

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371 €
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Anti-phospho-Smad3 (Ser423, Ser425)


Protein function: Receptor-​regulated SMAD (R-​SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-​beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-​beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-​1/SMAD site to regulate TGF-​beta-​mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-​ mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-​sensitive. Regulator of chondrogenesis and osteogenesis and inhibits early healing of bone fractures. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-​3-​3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium]
Immunogen: synthetic peptide corresponding to amino acids 417-​425 of human SMAD3 protein
MW: 48 kD


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Kat #: 600-401-919


Menge:
100 µg

Buy Bulk


Preis:
371 €
259 €

save money!


UniProt ID: P84022 (Protein knowledgebase)
Geninformationen: GeneID 4088

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Schlagworte:
Anti-​phospho-​Mad3, Anti-​phospho-​Smad3, Anti-​phospho-​SMAD3, Anti-​phospho-​MADH3, Anti-​phospho-​hMAD-​3, Anti-​phospho-​hSMAD3, Anti-​phospho-​JV15-​2, Anti-​phospho-​SMAD 3, Anti-​phospho-​MAD homolog 3, Anti-​phospho-​SMAD family member 3, antibody, antibodies, Antikörper
Image Art 600-401-919 Rockland Anti-​phospho-​Smad3 (Ser423, Ser425)

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