Antikörper Anti-phospho-Smad3 (Ser423, Ser425)

Antikörper Treffer 1

Rubrik: Modifikation:

Name/Antigen	KLON	WIRT	TYP	ISOTYP	SPEZ. REAKT.	FORMAT	ANWENDUNG	HERSTELLER	KAT #	MENGE	PREIS

Anti-phospho-Smad3 (Ser423, Ser425)		Rabbit > sec. Ab	Pab	IgG	human expected: Xenopus laevis, Xenopus tropicalis, zebrafish, rat, mouse, swine, bovine, chi		ELISA WB IHC	Rockland	600-401-919	100 µg Buy Bulk	353 € 317 €
Protein function: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF- mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-sensitive. Regulator of chondrogenesis and osteogenesis and inhibits early healing of bone fractures. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium] Immunogen: synthetic peptide corresponding to amino acids 417-425 of human SMAD3 protein MW: 48 kD Datenblatt ansehen Kat #: 600-401-919 Menge: 100 µg Buy Bulk Preis: 353 € 317 € UniProt ID: P84022 (Protein knowledgebase) Geninformationen: GeneID 4088 Passende, verwandte Produkte Antikörper-Konjugations-Kits Schlagworte: Anti-phospho-Mad3, Anti-phospho-Smad3, Anti-phospho-SMAD3, Anti-phospho-MADH3, Anti-phospho-hMAD-3, Anti-phospho-hSMAD3, Anti-phospho-JV15-2, Anti-phospho-SMAD 3, Anti-phospho-MAD homolog 3, Anti-phospho-SMAD family member 3, antibody, antibodies, Antikörper Loading ... zurück							Weitere Produkte für dieses Protein: Antibodies Anti-phospho-Smad2/3 (Thr8), Kat #: ABD-8A1001.50 Anti-phospho-Smad3 (Ser204), Kat #: ABD-8A1004.50 Anti-phospho-SMAD3 (Ser208), Kat #: WA-AP3249a Anti-phospho-Smad3 (Ser208), Kat #: ABD-8A1005.50 Anti-phospho-Smad3 (Ser213), Kat #: ABD-8A1007.50 Anti-phospho-SMAD3 (Ser213), Kat #: WA-AP3250a Anti-phospho-Smad3 (Ser423, Ser425), Kat #: 600-401-919S Anti-phospho-Smad3 (Ser425), Kat #: ABD-8A0031.50 Anti-phospho-SMAD3 (Thr179), Kat #: 600-401-C48S Anti-phospho-Smad3 (Thr179), Kat #: 600-401-C48 more siRNA SMAD3 predesign siRNA, Kat #: WA-RI14954 Chemicals & More SMAD3 Over-expression Lysate, Kat #: WA-LY12944a Peptides Phospho-SMAD3-S204 Antibody Blocking Peptide, Kat #: WA-BP3248a Phospho-SMAD3-S208 Antibody Blocking Peptide, Kat #: WA-BP3249a Phospho-SMAD3-S213 Antibody Blocking Peptide, Kat #: WA-BP3250a SMAD3 Antibody (Center D201) Blocking Peptide, Kat #: WA-BP6267a SMAD3 Antibody (Center N206) Blocking Peptide, Kat #: WA-BP6267b SMAD3-S208 Antibody Blocking Peptide, Kat #: WA-BP9995a Relevant Pathways: Cell cycle Endocytosis TGF-beta signaling pathway Adherens junction Chagas disease (American trypanosomiasis) HTLV-I infection Pathways in cancer Colorectal cancer Pancreatic cancer Products for: SMAD2_3 - mothers against decapentaplegic homolog 2/3 Antibodies (79) Enzymes & Proteins (1) Peptides (11) Primers (2)

Datenbank vom 22.05.2013, 17:22 Uhr

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