Anti-phospho-Histone H2AvD (Ser137)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-914 100 µg - -

6 - 10 business days*

684.00€
 
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.... more
Product information "Anti-phospho-Histone H2AvD (Ser137)"
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repressive state of homeotic genes of the animal throughout development. Required for histone H3 'Lys-9' methylation and histone H4 'Lys-12' acetylation, two modifications that are essential for heterochromatin formation. Also involved in DNA double strand break (DSB) repair. Essential for early development. [The UniProt Consortium]
Keywords: Anti-phospho-H2AvD, Anti-phospho-H2A.Z, Anti-phospho-His2Av, Anti-phospho-CG5499, Anti-phospho-H2A.F/Z, Anti-phospho-Histone H2A.v
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-914

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: Drosophila
Immunogen: synthetic peptide corresponding to amino acids 132-141 of Drosophila melanogaster H2AvD protein
MW: 14 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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