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Anti-NOXO1

ART NR.: 600-401-899 (100 µg)

Hersteller: Rockland

Datenblatt

Anwendungen: ELISA, WB, IF

Format: affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human

Immunogen: synthetic peptide corresponding to amino acids 238-252 of human NOXO1 protein

UniProt ID: Q8NFA2
Suche mit UniProt ID

Geninformationen: GeneID 124056

Schlagworte: Anti-NOXO1, Anti-P41NOX, Anti-Nox organizer 1, Anti-Nox-organizing protein 1, Anti-NADPH oxidase organizer 1, Anti-NADPH oxidase regulatory protein, Anti-SH3 and PX domain-containing protein 5

100 µg

371 €

333 €

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Bemerkungen: Protein function: Constitutively potentiates the superoxide-generating activity of NOX1 and NOX3 and is required for the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. Isoform 3 is more potent than isoform 1 in activating NOX3. Together with NOXA1, may also substitute to NCF1/p47phox and NCF2/p67phox in supporting the phagocyte NOX2/gp91phox superoxide-generating activity. [The UniProt Consortium]

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