Anti-AGAP2

Anti-AGAP2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
200-401-946 100 µg - -

6 - 10 business days*

684.00€
 
Protein function: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong... more
Product information "Anti-AGAP2"
Protein function: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion. [The UniProt Consortium]
Keywords: Anti-PIKE, Anti-AGAP2, Anti-GGAP2, Anti-AGAP-2, Anti-Cnt-g1, Anti-CENTG1, Anti-Centaurin-gamma-1, Anti-Phosphatidylinositol 3-kinase enhancer, Anti-GTP-binding and GTPase-activating protein 2, Anti-Arf-GAP with GTPase
Supplier: Rockland Immunochemicals
Supplier-Nr: 200-401-946

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: recombinant protein corresponding to amino acids 1-836 of human AGAP2 protein
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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