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Anti-EYA2 (IHC)

ART NR.: IHC-00736 (100 µl)

Hersteller: Bethyl

Datenblatt

Anwendungen: IHC

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human (expected: bovine, horse, orangutan, rhesus monkey, gorilla, chimpanzee, tasmanian devil, white-tufted-ear marmoset, crab-eating macaque, gray short-tailed opossum, small-eared galago, little brown bat, northern white-cheeked gibbon)

Immunogen: Synthetic peptide. The epitope recognized by IHC-00736 maps to a region between residue 100 and 150 of human eyes absent homolog 2 using the numbering given in entry NP_005235.3 (GeneID 2139).

UniProt ID: O00167
Suche mit UniProt ID

Geninformationen: GeneID 2139

Schlagworte: Anti-EAB1, Anti-EYA2, EC=3.1.3.48, Anti-Eyes absent homolog 2

IHC-00736

100 µl

401 €

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Bemerkungen: EYA2 (eyes absent homolog 2) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX. EYA2 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA2 coactivates SIX1. Together with SIX1 and DACH2 EYA2 seems to be involved in myogenesis. EYA2 may be involved in development of the eye. Alternative names for EYA2 include EAB1. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O00167]

Spezifikationen

bethyl_datasheet_parse.php?nr=IHC-00736&ak=1
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