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Anti-SPF45 (IHC)

ART NR.: IHC-00703 (100 µl)

Hersteller: Bethyl

Datenblatt

Anwendungen: IHC

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human, mouse (expected: rat, X. laevis, bovine, dog, guinea pig, swine, panda, orangutan, rhesus monkey, chimpanzee, tasmanian devil, white-tufted-ear marmoset, crab-eating macaque, european domestic ferret, northern white-cheeked gibbon)

Immunogen: synthetic peptide

UniProt ID: Q96I25
Suche mit UniProt ID

Geninformationen: GeneID 84991

Schlagworte: Anti-RBM17, Anti-SPF45, Anti-Splicing factor 45, Anti-45 kDa-splicing factor, Anti-RNA-binding motif protein 17

IHC-00703

100 µl

401 €

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Bemerkungen: Splicing factor 45 (SPF45) is an RNA splicing factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. SPF45 is involved in the regulation of alternative splicing and the utilization of cryptic splice sites. It has been shown to promote the utilization of a cryptic splice site created by the beta-110 mutation in the human beta-thalassemia gene. The resulting frameshift leads to sickle cell anemia. SPF45 is also known as RNA-binding motif protein 17, RBM17, and 45 kDa splicing factor. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96125]

Spezifikationen

bethyl_datasheet_parse.php?nr=IHC-00703&ak=1
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