Anti-Cyclin C (IHC)

Anti-Cyclin C (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00592-T 10 µl (1 µg) -

2 - 8 business days*

164.00€
IHC-00592 100 µl (10 µg) -

2 - 8 business days*

623.00€
 
Protein function: Component of the Mediator complex, a coactivator involved in regulated gene... more
Product information "Anti-Cyclin C (IHC)"
Protein function: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. [The UniProt Consortium]
Keywords: Anti-CCNC, Anti-hSRB11, Anti-Cyclin-C, Anti-SRB11 homolog
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00592

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, rat, chicken, turkey, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, monkey, gorilla, chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by IHC-00592 maps to a region between residue 244 and 294 of human cyclin C using the numbering given in entry NP_005181.2 (GeneID 892).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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