Anti-QKI (IHC)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
IHC-00574-T	10 µl (2500 ng)		-		2 - 8 business days*		164.00€
IHC-00574	100 µl (25 µg)		-		2 - 8 business days*		623.00€

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Protein function: RNA-binding protein that plays a central role in myelinization... more

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Product information "Anti-QKI (IHC)"

Protein function: RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)- UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor. [The UniProt Consortium]

Keywords:	Anti-QKI, Anti-Hqk, Anti-HKQ, Anti-HqkI, Anti-Protein quaking
Supplier:	Bethyl Laboratories
Supplier-Nr:	IHC-00574

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, zebrafish, X. laevis, chicken, bovine, dog, horse, pig, cat, orangutan, monkey, gorilla, chimpanzee)
Immunogen:	synthetic peptide. The epitope recognized by IHC-00574 maps to the C-terminus of isoform 5 of human quaking homolog according to entry AAH19917.1 (GeneID 9444).
Format:	Antigen Affinity Purified