Anti-MKRN1 (IHC)

Anti-MKRN1 (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00492-T 10 µl (1 µg) -

2 - 8 business days*

164.00€
IHC-00492 100 µl (10 µg) -

2 - 8 business days*

623.00€
 
Protein function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties... more
Product information "Anti-MKRN1 (IHC)"
Protein function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription. [The UniProt Consortium]
Keywords: Anti-MKRN1, Anti-RNF61, EC=2.3.2.27, Anti-RING finger protein 61, Anti-E3 ubiquitin-protein ligase makorin-1, Anti-RING-type E3 ubiquitin transferase makorin-1
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00492

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, monkey, gorilla, chimpanzee, chinese hamster)
Immunogen: synthetic peptide. The epitope recognized by IHC-00492 maps to a region between residue 432 and the C-terminus (residue 482) of human makorin, ring finger protein, 1 using the numbering given in entry NP_038474.1 (GeneID 23608).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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