- Search results for IHC-00490
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26 products were found matching "IHC-00490"!
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Item number: IHC-00409-T
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Keywords: | Anti-RPA1, Anti-REPA1 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00491
Protein function: Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10....
Keywords: | Anti-SFRS8, Anti-SFSWAP, Anti-Splicing factor, arginine/serine-rich 8, Anti-Suppressor of white apricot protein homolog,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00492
Protein function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions....
Keywords: | Anti-MKRN1, Anti-RNF61, EC=2.3.2.27, Anti-RING finger protein 61, Anti-E3 ubiquitin-protein ligase makorin-1,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00493
Protein function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. [The UniProt Consortium]
Keywords: | Anti-MKRN2, Anti-RNF62, Anti-HSPC070, EC=2.3.2.27, Anti-RING finger protein 62, Anti-RING-type E3 ubiquitin transferase... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00494
Protein function: Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. [The UniProt Consortium]
Keywords: | Anti-DOT1L, Anti-KIAA1814, EC=2.1.1.43, Anti-H3-K79-HMTase, Anti-DOT1-like protein, Anti-Lysine N-methyltransferase 4,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00495
Protein function: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1,...
Keywords: | Anti-DTL, Anti-CDT2, Anti-Denticleless protein homolog, Anti-DDB1- and CUL4-associated factor 2, Anti-Lethal(2)... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00496
Protein function: Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles. Regulates cilium formation and structure. [The UniProt Consortium]
Keywords: | Anti-HSET, Anti-KIFC1, Anti-Kinesin-like protein 2, Anti-Kinesin-like protein KIFC1, Anti-Kinesin-related protein HSET |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00498
Protein function: Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome...
Keywords: | Anti-BUB1B, Anti-BUBR1, Anti-hBUBR1, EC=2.7.11.1, Anti-Protein SSK1, Anti-Mitotic checkpoint kinase MAD3L,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00499
Protein function: Promotes guanine-nucleotide exchange on ARF1 and ARF3. Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP. Involved in vesicular trafficking. Required for the maintenance of Golgi structure, the function may be independent of its GEF activity. Required for the maturaion of...
Keywords: | Anti-ARFGEF1, Anti-ARFGEP1, Anti-p200 ARF-GEP1, Anti-Brefeldin A-inhibited GEP 1, Anti-p200 ARF guanine nucleotide... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: 0049-100
Recognizes akt dephosphorylated at Ser473. Does not cross-react with akt phosphorylated at Ser473.
Keywords: | Anti-PKB, Anti-PKB, Anti-AKT1, EC=2.7.11.1, Anti-RAC-PK-alpha, Anti-Protein kinase B, Anti-Proto-oncogene c-Akt,... |
Application: | WB, ELISA, IHC |
Host: | Mouse |
Species reactivity: | human, mouse, rat, dog |
322.00€
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Item number: ABE-44-1024-7
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a receptor on T Helper cells that functions as an immune checkpoint and downregulator of immune responses. Mutations in CTLA-4 are associated with insulin-dependent diabetes mellitus, Hashimoto's thyroiditis, Graves' disease, systemic lupus erythematosus (SLE),...
Keywords: | Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic T-lymphocyte-associated antigen... |
Application: | IHC |
Host: | Mouse |
Species reactivity: | human |
885.00€
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Item number: IHC-00460
Protein function: Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein...
Keywords: | Anti-HIF1A, Anti-bHLHe78, Anti-BHLHE78, Anti-HIF1-alpha, Anti-HIF-1-alpha, Anti-Member of PAS protein 1,... |
Application: | IHC, ICC-IF |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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