Anti-KARS (IHC)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00471-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00471 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2... more
Product information "Anti-KARS (IHC)"
Protein function: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (PubMed:9278442, PubMed:18029264, PubMed:18272479). When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages (PubMed:15851690). Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity (PubMed:5338216, PubMed:14975237, PubMed:19524539, PubMed:23159739). [The UniProt Consortium]
Keywords: Anti-KARS, Anti-LysRS, Anti-KIAA0070, Anti-Lysine--tRNA ligase, Anti-Lysyl-tRNA synthetase
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00471

Properties

Application: IHC, IHC-IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: orangutan, monkey, gorilla, chimpanzee, northern white-cheeked gibbon, african elephant, crab-eating macaque)
Immunogen: synthetic peptide. The epitope recognized by IHC-00471 maps to a region between residue 550 and the C-terminus (residue 597) of human Lysyl-tRNA Synthetase using the numbering given in entry NP_005539.1 (GeneID 3735).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-KARS (IHC)"
Write a review
or to review a product.
Viewed