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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
IHC-00467-T | 10 µl (2500 ng) | - |
2 - 8 business days* |
164.00€
|
|||
IHC-00467 | 100 µl (25 µg) | - |
2 - 8 business days* |
623.00€
|
Protein function: Catalyzes the 2 serial methylation steps for the conversion of the... more
Product information "Anti-PIMT (IHC)"
Protein function: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation. [The UniProt Consortium]
Keywords: | Anti-TGS1, Anti-PIMT, Anti-PIPMT, Anti-HCA137, EC=2.1.1.-, Anti-CLL-associated antigen KW-2, Anti-Trimethylguanosine synthase, Anti-Cap-specific guanine-N2 methyltransferase, Anti-Hepatocellular carcinoma-associated antigen 137 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | IHC-00467 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: gorilla, chimpanzee) |
Immunogen: | synthetic peptide. The epitope recognized by IHC-00467 maps to a region between residue 150 and 200 of human PRIP-Interacting Protein with Methyltransferase Domain using the numbering given in entry NP_079107.5 (GeneID 96764). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K14292 | Matching products |
UniProt ID : | Q96RS0 | Matching products |
Gene ID | GeneID 96764 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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