Anti-PIMT (IHC)

Anti-PIMT (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00467-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00467 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Catalyzes the 2 serial methylation steps for the conversion of the... more
Product information "Anti-PIMT (IHC)"
Protein function: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation. [The UniProt Consortium]
Keywords: Anti-TGS1, Anti-PIMT, Anti-PIPMT, Anti-HCA137, EC=2.1.1.-, Anti-CLL-associated antigen KW-2, Anti-Trimethylguanosine synthase, Anti-Cap-specific guanine-N2 methyltransferase, Anti-Hepatocellular carcinoma-associated antigen 137
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00467

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: gorilla, chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by IHC-00467 maps to a region between residue 150 and 200 of human PRIP-Interacting Protein with Methyltransferase Domain using the numbering given in entry NP_079107.5 (GeneID 96764).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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