23 products were found matching "IHC-00462"!

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Anti-CHD8 (IHC)
Anti-CHD8 (IHC)

Item number: IHC-00246-T

Protein function: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation...
Keywords: Anti-CHD-8, Anti-HELSNF1, Anti-ATP-dependent helicase CHD8, Anti-Helicase with SNF2 domain 1,...
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-RAP1 (IHC)
Anti-RAP1 (IHC)

Item number: IHC-00426-T

Protein function: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does...
Keywords: Anti-hRap1, Anti-DRIP5, Anti-PP8000, Anti-TERF2IP, Anti-RAP1 homolog, Anti-TRF2-interacting telomeric protein 1,...
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-FUSIP1 (IHC)
Anti-FUSIP1 (IHC)

Item number: IHC-00642-T

Protein function: Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing (PubMed:11684676, PubMed:12419250, PubMed:14765198). Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70 (PubMed:14765198). Required for splicing repression in M-phase cells and...
Keywords: Anti-TASR, Anti-SRrp40, Anti-FUSIP1, Anti-SRSF10, Anti-Splicing factor SRp38, Anti-TLS-associated SR protein, Anti-40 kDa...
Application: IHC, IHC-IF
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-FANCD2 (IHC)
Anti-FANCD2 (IHC)

Item number: IHC-00624-T

Protein function: Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon...
Keywords: Anti-FACD, Anti-FANCD2, Anti-Protein FACD2, Anti-Fanconi anemia group D2 protein
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-BRG1/SMARCA4 (IHC)
Anti-BRG1/SMARCA4 (IHC)

Item number: IHC-00466

Protein function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an...
Keywords: Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
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Anti-HIF1-alpha (IHC)
Anti-HIF1-alpha (IHC)

Item number: IHC-00460

Protein function: Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein...
Keywords: Anti-HIF1A, Anti-bHLHe78, Anti-BHLHE78, Anti-HIF1-alpha, Anti-HIF-1-alpha, Anti-Member of PAS protein 1,...
Application: IHC, ICC-IF
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-RAP80 (IHC)
Anti-RAP80 (IHC)

Item number: IHC-00461

Protein function: Ubiquitin-binding protein (PubMed:24627472). Specifically recognizes and binds 'Lys-63'-linked ubiquitin (PubMed:19328070, Ref.37). Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the...
Keywords: Anti-UIMC1, Anti-RAP80, Anti-BRCA1-A complex subunit RAP80, Anti-Receptor-associated protein 80, Anti-Retinoid X...
Application: IHC, IHC-IF
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-TCF12 (IHC)
Anti-TCF12 (IHC)

Item number: IHC-00464

Protein function: Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). [The UniProt Consortium]
Keywords: Anti-TCF12, Anti-TCF-12, Anti-BHLHB20, Anti-bHLHb20, Anti-E-box-binding protein, Anti-Transcription factor 12,...
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
Anti-Histone H3 (IHC)
Anti-Histone H3 (IHC)

Item number: IHC-00465

Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA...
Keywords: Anti-H3FL, Anti-H3FF, Anti-H3FK, Anti-H3FI, Anti-H3FB, Anti-H3FD, Anti-H3FC, Anti-H3FJ, Anti-H3FH, Anti-H3FA,...
Application: IHC, IHC-IF
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
Review
Anti-PIMT (IHC)
Anti-PIMT (IHC)

Item number: IHC-00467

Protein function: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of...
Keywords: Anti-TGS1, Anti-PIMT, Anti-PIPMT, Anti-HCA137, EC=2.1.1.-, Anti-CLL-associated antigen KW-2, Anti-Trimethylguanosine...
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-USP34 (IHC)
Anti-USP34 (IHC)

Item number: IHC-00468

Protein function: Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to...
Keywords: Anti-USP34, Anti-KIAA0570, EC=3.4.19.12, Anti-Ubiquitin thioesterase 34, Anti-Deubiquitinating enzyme 34, Anti-Ubiquitin...
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-PPP4R3 Alpha (IHC)
Anti-PPP4R3 Alpha (IHC)

Item number: IHC-00469

Protein function: Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and...
Keywords: Anti-MSTP033, Anti-KIAA2010, Anti-SMEK homolog 1, Anti-Serine/threonine-protein phosphatase 4 regulatory subunit 3A
Application: IHC, IHC-IF
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
Review
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