Anti-E2F1 (IHC)

Anti-E2F1 (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00459-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00459 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Transcription activator that binds DNA cooperatively with DP proteins through... more
Product information "Anti-E2F1 (IHC)"
Protein function: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812). [The UniProt Consortium]
Keywords: Anti-PBR3, Anti-E2F1, Anti-E2F-1, Anti-RBBP3, Anti-RBBP-3, Anti-RBAP-1, Anti-pRB-binding protein E2F-1, Anti-Transcription factor E2F1, Anti-Retinoblastoma-binding protein 3, Anti-Retinoblastoma-associated protein 1
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00459

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: synthetic peptide. The epitope recognized by ihc-00459 maps to a region between residue 300 and 350 of human E2F Transcription Factor 1 using the numbering given in entry NP_005216.1 (GeneID 1869).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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