Anti-DDX20 (IHC)

Anti-DDX20 (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00449-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00449 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear... more
Product information "Anti-DDX20 (IHC)"
Protein function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs). [The UniProt Consortium]
Keywords: Anti-DP103, Anti-DDX20, Anti-Gemin-3, EC=3.6.4.13, Anti-Component of gems 3, Anti-DEAD box protein 20, Anti-DEAD box protein DP 103, Anti-Probable ATP-dependent RNA helicase DDX20
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00449

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: horse, pig, panda, orangutan, monkey, gorilla, chimpanzee, hirteen-lined ground squirrel, small-eared galago)
Immunogen: synthetic peptide. The epitope recognized by IHC-00449 maps to a region between residues 600 and 650 of human DEAD (Asp-Glu-Ala-Asp) Box 20 using the numbering given in entry NP_009135.3 (GeneID 11218).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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