Anti-MAML1 (IHC)

Anti-MAML1 (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00445-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00445 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to... more
Product information "Anti-MAML1 (IHC)"
Protein function: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions. [The UniProt Consortium]
Keywords: Anti-Mam-1, Anti-Mastermind-like protein 1
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00445

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by IHC-00445 maps to a region between residue 75 and 125 of human Mastermind-like 1 using the numbering given in entry NP_055572.1 (GeneID 9794).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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