- Search results for IHC-00438
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30 products were found matching "IHC-00438"!
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Item number: IHC-00348-T
Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring...
Keywords: | Anti-hAgo, Anti-hCdc4, Anti-SEL-10, Anti-F-box protein FBX30, Anti-Archipelago homolog, Anti-F-box/WD repeat-containing... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00384-T
Protein function: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to...
Keywords: | Anti-NELFB, Anti-COBRA1, Anti-NELF-B, Anti-Cofactor of BRCA1, Anti-Negative elongation factor B |
Application: | IHC, IHC-IF |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: 030438.100
MDM4, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in...
Keywords: | Anti-MDMX, Anti-MDM4, Anti-Protein Mdm4, Anti-Protein Mdmx, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,... |
Application: | ELISA, IHC, WB |
Host: | Mouse |
Species reactivity: | human |
682.00€
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Item number: 040438.200
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as...
Keywords: | Anti-Pkacb, Anti-Prkacb, Anti-PKA C-beta, EC=2.7.11.11, Anti-cAMP-dependent protein kinase catalytic subunit beta |
Application: | ELISA, IHC, WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
728.00€
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Item number: IHC-00431
Protein function: Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo- and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially double-stranded DNA with a preference for 5'- single-stranded DNA overhangs. Is involved in several...
Keywords: | Anti-DBX, Anti-HLP2, Anti-DDX3X, EC=3.6.4.13, Anti-DEAD box, X isoform, Anti-Helicase-like protein 2, Anti-ATP-dependent... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00439
Protein function: E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. Mediates monoubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81',...
Keywords: | Anti-Mule, Anti-LASU1, Anti-HUWE1, Anti-URE-B1, Anti-HectH9, Anti-ARF-BP1, Anti-HSPC272, Anti-KIAA0312, EC=2.3.2.26,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00430
Protein function: In the process of mRNA degradation, plays a role in mRNA decapping (PubMed:16364915). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts (PubMed:26098573). [The UniProt Consortium]
Keywords: | Anti-DDX6, Anti-HLR2, Anti-Oncogene RCK, Anti-DEAD box protein 6, Anti-ATP-dependent RNA helicase p54, Anti-Probable... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00432
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
Keywords: | Anti-KRS1, Anti-STK3, EC=2.7.11.1 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00433
Protein function: Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3- phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex....
Keywords: | Anti-SNX1, Anti-Sorting nexin-1 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00434
Protein function: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5,...
Keywords: | Anti-AF6q21 protein, Anti-Forkhead box protein O3, Anti-Forkhead in rhabdomyosarcoma-like 1 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00436
Protein function: Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). [The UniProt Consortium]
Keywords: | Anti-PXN, Anti-Paxillin |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: AG-25B-0043-C050
GLUT2 belongs the family of glucose transporters (GLUTs, encoded by the SLC2A genes), which comprises 14 isoforms. GLUT2 has a uniquely low affinity for glucose (Km ~ 17mmol/l), and can also use mannose, galactose and fructose as low affinity substrates, it has, however, a high affinity for glucosamine (Km ~...
Keywords: | Anti-GLUT-2, Anti-Glucose transporter type 2, liver, Anti-Solute carrier family 2, facilitated glucose transporter member 2 |
Application: | WB, IHC, IP |
Host: | Rabbit |
Species reactivity: | rat |
220.00€
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