- Search results for IHC-00435
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26 products were found matching "IHC-00435"!
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Item number: IHC-00453-T
Protein function: Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals (PubMed:25416785, PubMed:28596309). Thus, functions as a protein deglycase that repairs methylglyoxal- and...
Keywords: | Anti-DJ-1, Anti-Oncogene DJ1, Anti-Protein DJ-1, Anti-Maillard deglycase, Anti-Parkinson disease protein 7,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: 030435.100
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the...
Keywords: | Anti-MCM2, Anti-BM28, EC=3.6.4.12, Anti-Nuclear protein BM28, Anti-DNA replication licensing factor MCM2,... |
Application: | ELISA, FC, IHC, WB |
Host: | Mouse |
Species reactivity: | human, monkey, mouse, rat |
719.00€
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Item number: IHC-00431
Protein function: Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo- and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially double-stranded DNA with a preference for 5'- single-stranded DNA overhangs. Is involved in several...
Keywords: | Anti-DBX, Anti-HLP2, Anti-DDX3X, EC=3.6.4.13, Anti-DEAD box, X isoform, Anti-Helicase-like protein 2, Anti-ATP-dependent... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00439
Protein function: E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. Mediates monoubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81',...
Keywords: | Anti-Mule, Anti-LASU1, Anti-HUWE1, Anti-URE-B1, Anti-HectH9, Anti-ARF-BP1, Anti-HSPC272, Anti-KIAA0312, EC=2.3.2.26,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00430
Protein function: In the process of mRNA degradation, plays a role in mRNA decapping (PubMed:16364915). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts (PubMed:26098573). [The UniProt Consortium]
Keywords: | Anti-DDX6, Anti-HLR2, Anti-Oncogene RCK, Anti-DEAD box protein 6, Anti-ATP-dependent RNA helicase p54, Anti-Probable... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00432
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
Keywords: | Anti-KRS1, Anti-STK3, EC=2.7.11.1 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00433
Protein function: Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3- phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex....
Keywords: | Anti-SNX1, Anti-Sorting nexin-1 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00434
Protein function: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5,...
Keywords: | Anti-AF6q21 protein, Anti-Forkhead box protein O3, Anti-Forkhead in rhabdomyosarcoma-like 1 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00436
Protein function: Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). [The UniProt Consortium]
Keywords: | Anti-PXN, Anti-Paxillin |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: AG-20B-0043-C100
Neutrophils are key components of the inflammatory response and as such contribute to the killing of microorganisms. In addition, recent evidence suggests their involvement in the development of the immune response. The Nimp-R14 mAb displays features of an optimal reagent allowing the selective depletion of mouse...
Application: | FC, IHC, ICC, FA (Blocking) |
Host: | Rat |
Species reactivity: | mouse |
308.00€
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Item number: ABE-44-1024-7
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a receptor on T Helper cells that functions as an immune checkpoint and downregulator of immune responses. Mutations in CTLA-4 are associated with insulin-dependent diabetes mellitus, Hashimoto's thyroiditis, Graves' disease, systemic lupus erythematosus (SLE),...
Keywords: | Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic T-lymphocyte-associated antigen... |
Application: | IHC |
Host: | Mouse |
Species reactivity: | human |
885.00€
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Item number: ABE-44-1023-0.1
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a receptor on T Helper cells that functions as an immune checkpoint and downregulator of immune responses. Mutations in CTLA-4 are associated with insulin-dependent diabetes mellitus, Hashimoto's thyroiditis, Graves' disease, systemic lupus erythematosus (SLE),...
Keywords: | Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic T-lymphocyte-associated antigen... |
Application: | IHC |
Host: | Mouse |
Species reactivity: | human |
620.00€
*