- Search results for IHC-00421
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16 products were found matching "IHC-00421"!
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Item number: BPS-100421
Human secreted Siglec8, also known as Sialic Acid Binding Ig Like Lectin 8, and SAF2, GenBank Accession No. NM_014442, a.a. 17-363, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag(TM) expressed in a HEK293 cell expression system. MW = 67 kDa. This protein runs at a higher MW by...
Keywords: | SAF2, SAF-2, SIGLEC8, Siglec-8, Sialoadhesin family member 2, Sialic acid-binding Ig-like lectin 8, |
Application: | Immunotherapy studies |
Expressed in: | human cells |
Origin: | human |
MW: | 67 kD |
474.00€
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Item number: IHC-00142-T
Protein function: Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing. Can function as an estrogen receptor corepressor and can...
Keywords: | Anti-HAP, Anti-SAFB, Anti-SAF-B, Anti-SAF-B1, Anti-Scaffold attachment factor B1, Anti-HSP27 ERE-TATA-binding protein,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00412-T
Protein function: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore- spindle attachment and inhibits the activity of the...
Keywords: | Anti-MAD2, Anti-HsMAD2, Anti-MAD2L1, Anti-MAD2-like protein 1, Anti-Mitotic arrest deficient 2-like protein 1,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00241-T
Protein function: Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. Acts as the scaffold of PML-NBs allowing other proteins...
Keywords: | Anti-PML, Anti-MYL, Anti-Protein PML, Anti-RING finger protein 71, Anti-Promyelocytic leukemia protein, Anti-Tripartite... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00214-T
Protein function: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also...
Keywords: | Anti-SF3B1, Anti-SAP155, Anti-SAP 155, Anti-SF3b155, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: AG-20B-0042-C100
Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response...
Keywords: | Anti-CASP1, Anti-CASP-1, Anti-ICE, EC=3.4.22.36 |
Application: | WB, IHC, IP |
Host: | Mouse |
Species reactivity: | mouse |
440.00€
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Item number: IHC-00422
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Keywords: | Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,... |
Application: | IHC, IHC-IF |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: 040421-HRP.200
PRDX6 is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell, it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation...
Application: | ELISA, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
993.00€
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Item number: 040421.200
PRDX6 is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell, it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation...
Application: | ELISA, FC, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
728.00€
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Item number: IHC-00429
Protein function: Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient- insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by...
Keywords: | Anti-hAVO3, Anti-AVO3 homolog, Anti-Rapamycin-insensitive companion of mTOR |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00420
Protein function: Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a...
Keywords: | Anti-UBA52, Anti-UBCEP2 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00423
Protein function: Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6. [The UniProt Consortium]
Keywords: | Anti-MTA3, Anti-KIAA1266, Anti-Metastasis-associated protein MTA3 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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