- Search results for IHC-00418
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31 products were found matching "IHC-00418"!
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Item number: IHC-00481-T
The epitope recognized by IHC-00481 maps to a region between residue 1010 and the C-terminus (residue 1058) fo human Gem (nuclear organelle) Associated Protein 4 using the numbering given in entry NP_056536.1 (GeneID 50628).
Keywords: | Anti-Gem (Nuclear organelle) associated protein 4 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00148-T
Protein function: Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR...
Keywords: | Anti-UBCE7, Anti-UbcH7, Anti-L-UBC, Anti-UBE2L3, Anti-Ubiquitin-protein ligase L3, Anti-Ubiquitin carrier protein L3,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00184-T
Protein function: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear...
Keywords: | Anti-MAD1, Anti-hMAD1, Anti-HsMAD1, Anti-MAD1L1, Anti-MAD1-like protein 1, Anti-Tax-binding protein 181, Anti-Mitotic... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: BOT-BNC400418-100
Recognizes a protein of 55 kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin's disease. It is uniformly...
Keywords: | Fascin-1(FSCN1/418), CF640R conjugate, 0.1mg/mL, |
Application: | FC, intracellular (verif.), IF (verif.), IHC (paraffin) (verif.), WB (verif.) |
From 274.00€
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Item number: IHC-00419
Protein function: Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by...
Keywords: | Anti-ZEB1, Anti-AREB6, Anti-TCF-8, Anti-Transcription factor 8, Anti-Negative regulator of IL2, Anti-NIL-2-A zinc finger... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00412
Protein function: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore- spindle attachment and inhibits the activity of the...
Keywords: | Anti-MAD2, Anti-HsMAD2, Anti-MAD2L1, Anti-MAD2-like protein 1, Anti-Mitotic arrest deficient 2-like protein 1,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00411-T
Protein function: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0...
Keywords: | Anti-MTr1, Anti-CMTR1, Anti-ISG95, Anti-hMTr1, Anti-FTSJD2, EC=2.1.1.57, Anti-Cap methyltransferase 1, Anti-Cap1... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00413
Protein function: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1...
Keywords: | Anti-Int7, Anti-INTS7, Anti-C1orf73, Anti-Integrator complex subunit 7 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00414
Protein function: Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and...
Keywords: | Anti-AKI1, Anti-CC2D1A, Anti-Freud-1, Anti-Akt kinase-interacting protein 1, Anti-Putative NF-kappa-B-activating protein... |
Application: | IHC, IHC-IF |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00415
Protein function: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1...
Keywords: | Anti-Int8, Anti-INTS8, Anti-C8orf52, Anti-Protein kaonashi-1, Anti-Integrator complex subunit 8 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00416
Protein function: Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific...
Keywords: | Anti-GL002, Anti-C11orf30, Anti-BRCA2-interacting transcriptional repressor EMSY |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00417
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Keywords: | Anti-RPA2, Anti-REPA2, Anti-RP-A p34, Anti-RP-A p32, Anti-RF-A protein 2, Anti-Replication factor A protein 2,... |
Application: | IHC, IHC-IF |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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