Anti-CC2D1A (IHC)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00414-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00414 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Transcription factor that binds specifically to the DRE (dual repressor... more
Product information "Anti-CC2D1A (IHC)"
Protein function: Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses. Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis. [The UniProt Consortium]
Keywords: Anti-AKI1, Anti-CC2D1A, Anti-Freud-1, Anti-Akt kinase-interacting protein 1, Anti-Putative NF-kappa-B-activating protein 023N, Anti-FRE under dual repression-binding protein 1, Anti-Coiled-coil and C2 domain-containing protein 1A
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00414

Properties

Application: IHC, IHC-IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, orangutan, gorilla, chimpanzee)
Immunogen: synthetic peptide. The epitope recognized byIHC-00414 maps to a region between residues 1 and 50 of human Coiled-coil and C2 Domain Containing 1A using the numbering given in TrEMBL entry Q6P1N0 (GeneID 54862).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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