- Search results for IHC-00410
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37 products were found matching "IHC-00410"!
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Item number: IHC-00041-T
Protein function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two...
Keywords: | Anti-MCM5, Anti-CDC46, Anti-P1-CDC46, EC=3.6.4.12, Anti-CDC46 homolog, Anti-DNA replication licensing factor MCM5 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00140-T
Protein function: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1...
Keywords: | Anti-BANP, Anti-BEND1, Anti-Protein BANP, Anti-BEN domain-containing protein 1, Anti-Btg3-associated nuclear protein,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00104-T
Protein function: Involved in DNA damage response, activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371). Required for...
Keywords: | Anti-BAAT1, Anti-BRAT1, Anti-BRCA1-associated ATM activator 1, Anti-BRCA1-associated protein required for ATM activation... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: Cay500410-96
Collagen-induced arthritis (CIA) is an experimental autoimmune disease that is widely used as a model of human rheumatoid arthritis (RA) in the study of the pathogenic mechanisms of this disease and for testing potential therapeutics. Circulating levels of anti-type II collagen antibody are strongly associated with...
Keywords: | Autoimmune disease, Collagen-induced arthritis (CIA) |
Application: | EIA |
Species reactivity: | mouse |
506.00€
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Item number: BOT-BNC400410-100
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome...
Keywords: | MALT-1(MT1/410), CF640R conjugate, 0.1mg/mL, |
Application: | IHC (paraffin) (verif.), WB (verif.) |
From 274.00€
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Item number: AG-25B-0041-C050
GLUT2 belongs the family of glucose transporters (GLUTs, encoded by the SLC2A genes), which comprises 14 isoforms. GLUT2 has a uniquely low affinity for glucose (Km ~ 17mmol/l), and can also use mannose, galactose and fructose as low affinity substrates, it has, however, a high affinity for glucosamine (Km ~...
Keywords: | Anti-GLUT-2, Anti-Glucose transporter type 2, liver, Anti-Solute carrier family 2, facilitated glucose transporter member 2 |
Application: | WB, IHC, IP |
Host: | Rabbit |
Species reactivity: | human |
220.00€
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Item number: IHC-00419
Protein function: Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by...
Keywords: | Anti-ZEB1, Anti-AREB6, Anti-TCF-8, Anti-Transcription factor 8, Anti-Negative regulator of IL2, Anti-NIL-2-A zinc finger... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00412
Protein function: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore- spindle attachment and inhibits the activity of the...
Keywords: | Anti-MAD2, Anti-HsMAD2, Anti-MAD2L1, Anti-MAD2-like protein 1, Anti-Mitotic arrest deficient 2-like protein 1,... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00411-T
Protein function: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0...
Keywords: | Anti-MTr1, Anti-CMTR1, Anti-ISG95, Anti-hMTr1, Anti-FTSJD2, EC=2.1.1.57, Anti-Cap methyltransferase 1, Anti-Cap1... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: IHC-00413
Protein function: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1...
Keywords: | Anti-Int7, Anti-INTS7, Anti-C1orf73, Anti-Integrator complex subunit 7 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00414
Protein function: Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and...
Keywords: | Anti-AKI1, Anti-CC2D1A, Anti-Freud-1, Anti-Akt kinase-interacting protein 1, Anti-Putative NF-kappa-B-activating protein... |
Application: | IHC, IHC-IF |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: IHC-00415
Protein function: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1...
Keywords: | Anti-Int8, Anti-INTS8, Anti-C8orf52, Anti-Protein kaonashi-1, Anti-Integrator complex subunit 8 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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