31 products were found matching "IHC-00345"!

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Anti-WDR79 (IHC)
Anti-WDR79 (IHC)

Item number: IHC-00534-T

Protein function: Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of...
Keywords: Anti-TCAB1, Anti-WRAP53, Anti-WD repeat-containing protein 79, Anti-Telomerase Cajal body protein 1, Anti-WD...
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
Anti-DJ-1 (IHC)
Anti-DJ-1 (IHC)

Item number: IHC-00453-T

Protein function: Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals (PubMed:25416785, PubMed:28596309). Thus, functions as a protein deglycase that repairs methylglyoxal- and...
Keywords: Anti-DJ-1, Anti-Oncogene DJ1, Anti-Protein DJ-1, Anti-Maillard deglycase, Anti-Parkinson disease protein 7,...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
Review
Anti-IRAK4
Anti-IRAK4

Item number: 030345.100

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants...
Application: ELISA, FC, IHC, WB
Host: Mouse
Species reactivity: human, monkey, mouse
719.00€ *
Review
Anti-Cyclin E1 (IHC)
Anti-Cyclin E1 (IHC)

Item number: IHC-00341

Protein function: Essential for the control of the cell cycle at the G1/S (start) transition. [The UniProt Consortium]
Keywords: Anti-CCNE, Anti-CCNE1, Anti-G1/S-specific cyclin-E1
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
Anti-FBW7 (IHC)
Anti-FBW7 (IHC)

Item number: IHC-00348

Protein function: Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring...
Keywords: Anti-hAgo, Anti-hCdc4, Anti-SEL-10, Anti-F-box protein FBX30, Anti-Archipelago homolog, Anti-F-box/WD repeat-containing...
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
Anti-Flightless-1 (IHC)
Anti-Flightless-1 (IHC)

Item number: IHC-00340

Protein function: May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development. May play a role in regulation of cytoskeletal rearrangements...
Keywords: Anti-FLII, Anti-FLIL, Anti-Protein flightless-1 homolog
Application: IHC, IHC-IF
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
Anti-METTL3/MT-A70 (IHC)
Anti-METTL3/MT-A70 (IHC)

Item number: IHC-00342

Protein function: The METTL3-METTL14 heterodimer forms a N6- methyltransferase complex that methylates adenosine residues of some RNAs and regulates the circadian clock, differentiation of embryonic stem cells and primary miRNA processing (PubMed:22575960, PubMed:24284625, PubMed:25719671, PubMed:25799998,...
Keywords: Anti-MTA70, Anti-MT-A70, Anti-METTL3, Anti-hMETTL3, Anti-Methyltransferase-like protein 3,...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
Review
Anti-PHF8 (IHC)
Anti-PHF8 (IHC)

Item number: IHC-00343

Protein function: Histone lysine demethylase with selectivity for the di- and monomethyl states that plays a key role cell cycle progression, rDNA transcription and brain development. Demethylates mono- and dimethylated histone H3 'Lys-9' residue (H3K9Me1 and H3K9Me2), dimethylated H3 'Lys-27' (H3K27Me2) and...
Keywords: Anti-PHF8, Anti-KIAA1111, EC=1.14.11.27, Anti-PHD finger protein 8, Anti-Histone lysine demethylase PHF8
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
Review
Anti-XPA (IHC)
Anti-XPA (IHC)

Item number: IHC-00344

Protein function: Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD),...
Keywords: Anti-XPA, Anti-XPAC, Anti-DNA repair protein complementing XP-A cells, Anti-Xeroderma pigmentosum group A-complementing...
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
Anti-14-3-3 Sigma (IHC)
Anti-14-3-3 Sigma (IHC)

Item number: IHC-00346

Protein function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding...
Keywords: Anti-SFN, Anti-HME1, Anti-Stratifin, Anti-14-3-3 protein sigma, Anti-Epithelial cell marker protein 1
Application: IHC, IHC-IF
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
Anti-PUS1 (IHC)
Anti-PUS1 (IHC)

Item number: IHC-00347

Protein function: Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Involved in regulation of nuclear receptor activity possibly through pseudouridylation of SRA1 RNA. [The...
Keywords: Anti-PUS1, Anti-PP8985, EC=5.4.99.12, Anti-tRNA-uridine isomerase I, Anti-tRNA pseudouridylate synthase I, Anti-tRNA...
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
Anti-NUP50 (IHC)
Anti-NUP50 (IHC)

Item number: IHC-00349

Protein function: Component of the nuclear pore complex that has a direct role in nuclear protein import (PubMed:20016008). Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling (PubMed:20016008). Interacts with regulatory proteins of...
Keywords: Anti-NUP50, Anti-PRO1146, Anti-NPAP60L, Anti-Nucleoporin Nup50, Anti-50 kDa nucleoporin, Anti-Nuclear pore complex protein...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
Review
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