Anti-EPS15 (IHC)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00337-T 10 µl (1 µg) -

2 - 8 business days*

164.00€
IHC-00337 100 µl (10 µg) -

2 - 8 business days*

623.00€
 
Protein function: Involved in cell growth regulation. May be involved in the regulation of... more
Product information "Anti-EPS15 (IHC)"
Protein function: Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Plays a role in the assembly of clathrin-coated pits (CCPs). Acts as a clathrin adapter required for post-Golgi trafficking. Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta- 1 (ITGB1) and transferrin receptor (TFR), internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. [The UniProt Consortium]
Keywords: Anti-AF1P, Anti-EPS15, Anti-Protein AF-1p, Anti-Protein Eps15, Anti-Epidermal growth factor receptor substrate 15
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00337

Properties

Application: IHC, IHC-IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: orangutan, monkey, chimpanzee, northern white-cheeked gibbon, crab-eating macaque)
Immunogen: synthetic peptide. The epitope recognized by IHC-00337 maps to a region between residue 575 and 625 of human epidermal growth factor receptor pathway substrate 15 using the numbering given in entry NP_001972.1 (GeneID 2060).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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