Anti-USP5/IsoT (IHC)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00313-T 10 µl (1 µg) -

2 - 8 business days*

164.00€
IHC-00313 100 µl (10 µg) -

2 - 8 business days*

623.00€
 
Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference... more
Product information "Anti-USP5/IsoT (IHC)"
Protein function: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition. [The UniProt Consortium]
Keywords: Anti-ISOT, Anti-USP5, EC=3.4.19.12, Anti-Isopeptidase T, Anti-Ubiquitin thioesterase 5, Anti-Deubiquitinating enzyme 5, Anti-Ubiquitin carboxyl-terminal hydrolase 5, Anti-Ubiquitin-specific-processing protease 5
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00313

Properties

Application: IHC, IHC-IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: orangutan, monkey, gorilla, chimpanzee, northern white-cheeked gibbon, crab-eating macaque, white-tufted-ear marmoset)
Immunogen: synthetic peptide. The epitope recognized by IHC-00313 maps to a region between residue 375 and 425 of human ubiquitin specific peptidase 5 (isopeptidase T) using the numbering given in entry CAA62690.1 (GeneID 8078).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-USP5/IsoT (IHC)"
Write a review
or to review a product.
Viewed