Anti-KANK2/SIP (IHC)

Anti-KANK2/SIP (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00301-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00301 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Involved in transcription regulation by sequestering nuclear receptor... more
Product information "Anti-KANK2/SIP (IHC)"
Protein function: Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm, the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis, proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation. [The UniProt Consortium]
Keywords: Anti-SIP, Anti-KANK2, Anti-ANKRD25, Anti-SRC-interacting protein, Anti-SRC1-interacting protein, Anti-SRC-1-interacting protein, Anti-Matrix-remodeling-associated protein 3, Anti-Ankyrin repeat domain-containing protein 25
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00301

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: orangutan, monkey, gorilla, chimpanzee, northern white-cheeked gibbon, crab-eating macaque)
Immunogen: synthetic peptide. The epitope recognized by IHC-00301 maps to a region between residue 550 and 600 of human KN motif and ankyrin repeat domains 2 (SRC-1 interacting protein) using the numbering given in entry NP_056308.2 (GeneID 25959).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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