Anti-APC IHC Antibody, affinity purifie (IHC)

Anti-APC IHC Antibody, affinity purifie (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00252-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00252 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt... more
Product information "Anti-APC IHC Antibody, affinity purifie (IHC)"
Protein function: Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization. [The UniProt Consortium]
Keywords: Anti-APC, Anti-DP2.5, Anti-Protein APC, Anti-Deleted in polyposis 2.5, Anti-Adenomatous polyposis coli protein
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00252

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, rat, zebrafish, X. tropicalis, chicken, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, monkey, gorilla)
Immunogen: synthetic peptide. The epitope recognized by IHC-00252 maps to a region between residue 1 and 50 of human adenomatosis polyposis coli using the numbering given in entry NP_000029.2 (GeneID 324).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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